职 称：助理教授
所属科室：生物合成研究室
导师类别：博士生导师
九游官网下载的联系方式：jiameirong@imm.ac.cn
所属重点实验室：天然药物活性物质与功能国家重点实验室；
国家卫生健康委员会天然药物生物合成重点实验室；
中国医学科学院酶与天然药物生物催化重点实验室
贾美荣，课题组长，博导，北京市科技新星，本科毕业于山东大学药学院，博士毕业于美国iowa state university，在美国university of california, davis完成博士后研究。目前兼任《chinese journal of natural medicines》等杂志的青年编委, 《molecular plant》科学编辑。2021年作为中国医学科学院“高层次引进人才”，到北京协和医学院药物研究所工作，任课题组长。迄今在acs catalysis, metabolic engineering等国际著名期刊发表研究论文和论著20余篇。
药用植物来源的活性天然物质的挖掘、生物合成、结构优化和异源生产
1. 基于整合组学的活性天然产物的功能基因元件挖掘和生物功能鉴定
2. 基于计算机模拟和量子化学计算的生物酶催化机制阐明和功能设计改造
3. 基于多元底盘的活性天然产物的合成生物学研究
1. muchlinski a#, jia m#, tiedge k#, fell j, pelot k, chew l, davisson d, chen y, siegel j, lovell j, zerbe p. cytochrome p450-catalyzed biosynthesis of furanoditerpenoids in the bioenergy crop switchgrass (panicum virgatum l.). plant j, 2021, 108: 1053.
2. jasmonic acid transport in wound-induced systemic immunity. jia m. molecular plant. 2020, 13:1673.
3. switching on a nontraditional enzymatic base–deprotonation by serine in the ent-kaurene synthase from bradyrhizobium japonicum. jia m#, zhang y#, siegel jb, tantillo dj, peters rj. acs catal. 2019, 9:8867.
4. combinatorial biosynthesis and the basis for substrate promiscuity in class i diterpene synthases. jia m, mishra s, tufts s, jernigan r, peters rj. metab eng. 2019, 55:44.
5. changing face: a key residue for the addition of water by sclareol synthase. jia m, o’brien te, zhang y, siegel jb, tantillo dj, peters rj. acs catal. 2018, 8:3133.
6. extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis. jia m, potter kc, peters rj. metab eng. 2016, 37:24.
7. a pair of residues that interactively affect diterpene synthase product outcome. jia m, zhou k, tufts s, schulte s, peters rj.acs chem. biol. 2017, 12:862.
8. extending a single residue switch for abbreviating catalysis in plant ent-kaurene synthases. jia m, peters rj. frontiers in plant science. 2016, 7:1765.
9. cis or trans with class ii diterpene cyclases. jia m, peters rj. organic & biomolecular chemistry, 2017, 15:3158.
1. zhang y, jia m, gao w. synthetic biology of active compounds. in book: molecular pharmacognosy, second edition. edited by luqi huang, springer press. chapter 9, 2019, 267-292. print isbn 978-981-32-9033-4.
2. yang j, jia m, guo j. functional genome of medicinal plants. in book: molecular pharmacognosy, second edition. edited by luqi huang, springer press. chapter 7, 2019, 191-234. print isbn 978-981-32-9033-4.