侯琦，女，研究员，博士生导师。现就职于中国医学科学院药物研究所药理室，任抗炎免疫课题组组长。主要从事抗炎免疫药理学研究。科技部、卫生部、教育部重大科研项目以及国家自然科学基金项目的评审专家。近年来承担或参与国家自然科学基金面上项目等众多项科研项目，在apoptosis，jbc、jlr、jmc等期刊上发表研究论文30多篇，申请专利20多项，并获得科技奖励2项。
教育背景
2001/02 – 2003/05，南卡罗莱那医科大学（musc，usa），博士后
1997/9-2000/6, 中国医学科学院药物研究所，博士
1989/09 - 1991/06，山东大学医学院，硕士
1982/09-1987/06 滨州医学院，学士
工作经历
2007/03 - 至今，中国医学科学院药物研究所，研究员。
2003/5-2007/3，musc，usa，助理教授
1987/9-1997/6 潍坊医学院，天然药物与药理学研究室，副教授
1. 抗炎免疫药理学及其相关新药研究
2. 哮喘、copd炎症调控新靶点新机制研究
3. 风湿性、类风湿性以及骨关节炎药物筛选与发现研究
4. 再生障碍性贫血免疫病理机制及其调控药物研究
5. 基于靶标抗原-免疫磁珠的中药致敏原筛选与评价
1. pei ma#, shuyi li#, hui yang, jiqiao yuan, ziqian zhang, xuyu li, nan fang, mingbao lin* and qi hou*. comparative rna‐seq transcriptome analysis on pulmonary inflammation in a mouse model of asthma-copd overlap syndrome. frontiers in cell and developmental biology. 2021，doi: 10.3389/fcell.2021.628957.
2. shuyi li, hui yang, jiqiao yuan, ziqian zhang, xuyu li, nan fang, mingbao lin*, qi hou*. syk-targeted, a new 3-arylbenzofuran derivative eapp-2 blocks airway inflammation of asthma–copd overlap in vivo and in vitro. journal of inflammation research. 2021，14：2173-2185.
3. yasi ding#, weibin tang#, fei pei#, lixia fu, pei ma, jinye bai, mingbao lin*, yunbao liu*, qi hou*. brusatol derivative - 34 attenuates allergic airway inflammation via inhibition of the syk pathway. frontiers in pharmacology. 2021, doi: 10.3389/fphar.2021.587417.
4. hui yang# ,wei sun#,yan-nan fan, shu-yi li, ji-qiao yuan, zi-qian zhang, xu-yu li, ming-bao lin* , and qi hou*. perilla leaf extract attenuates asthma airway inflammation by blocking the syk pathway. mediators of inflammation. 2021，2021：6611219.
5. hui yang,wei sun, pei ma,chunsuo yao,yannan fan,shuyi li,jiqiao yuan,xuyu li, mingbao lin*,qi hou*. multiple components rapidly screened from perilla leaves attenuate asthma airway inflammation by synergistic targeting on syk. journal of inflammation research. 2020:13 897–911.
6. pei ma, lifeng yue, hui yang, yannan fan, jinye bai, shuyi li, jiqiao yuan, ziqian zhang, chunsuo yao, mingbao lin*, qi hou*. hondroprotective and anti-inflammatory effects of amurensin h by regulating tlr4/syk/nf-κb signals. j cell mol med. 2020;24:1958–1968
7. yannan fan, ziqian zhang, chunsuo yao, jinye bai, hui yang, pei ma, yiyao fan, shuyi li, jiqiao yuan, mingbao lin* and qi hou*. amurensin h, a derivative from resveratrol, ameliorates lipopolysaccharide / cigarette smoke‐induced airway inflammation by blocking the syk/nf-κb pathway. frontiers in pharmacology. 2019, 10: 1157.
8. hui yang#, jing guan#, pei ma, yannan fan, jinye bai, shuyi li, jiqiao yuan,yecheng jin, mingbao lin#*, jianmin zhang*, and qi hou*. beneficial effects of qingzixiaoban granule on henoch–sch¨onlein purpura nephritis mice through inhibiting immune complex deposition and th2 immunodeviation. ecam. 2019: 3050248.
9. yuanyuan zhuang#, jiabao liu#, pei ma#, jinye bai, yasi ding, hui yang, yannan fan, mingbao lin*, shuai li*, qi hou*. tamarixinin a alleviates joint destruction of rheumatoid arthritis by blockade of mapk and nf-κb activation. frontiers in pharmacology. 2017, 8: 538.
10. lingling xuan, rentao jiang, zhiyuan wu, honggan yi, chunsuo yao, qi hou*, chunfeng qu*. vam3, a compound derived from vitis amurensis rupr., attenuated colitis-related tumorigenesis by inhibiting nf-kappa b signaling pathway , frontiers in pharmacology, 2016.9.13, 7.
11. yunxiao li, ganggang y u, shaopeng yuan, chunting tan, jianlin xie, yasi ding, puqiao lian, lixia fu, qi hou*, bo xu*, haoyan wang*. 14,15- epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy, american journal of physiology-lung cellular and molecular physiology, 2016.11.1, 311(5): l970~l980.
12. junling zhang, xiaolei xue, xiaodan han, chunsuo yao, lu lu, deguan li, qi hou*, weimin miao, aimin meng*, saijun fan*. vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of nrf2-targeted genes , free radical biology and medicine, 2016.12, 101: 455~464.
