1978年11月出生，博士，研究员，博士生导师，天然药物活性物质与功能国家重点实验室课题组长，支部书记，办公室主任，北京药学会天然药物专业委员会委员。2007年获北京协和医学院博士学位，2008-2011年于美国密歇根州立大学作博士后。先后主持或参加科技部“重大新药创制”科技重大专项、国家自然科学基金、北京市科学基金及院所基金等10余项科技项目。在angew chim int edi, org lett，j nat prod等本领域重要期刊发表sci收录论文50余篇，申请专利25项，获授权专利10项。
特殊生境微生物中新颖结构活性分子的发现及其形成机制与作用机制研究。 重要中药药效物质发现及其与功效相关性研究。 基于天然产物的创新药物研究。
1. characterization and engineering of two highly paralogous sesquiterpene synthases reveal a regioselective reprotonation switch. dan ye, yizhen shao, wen-rui li, zhen-jia cui, ting gong, jin-ling yang, hai-qiang wang, jun-gui dai, ke-ping feng, ming ma, shuang-gang ma*, yun-bao liu*, ping zhu*, and shi shan yu*, angewandte chemie international edition, 2024, 7, e202315674.
2. muyocoxanthones o-s: undescribed xanthones with antioxidative damage bioactivity to cardiomyocytes from the endophytic fungus muyocopron laterale. hai-yan cao, sen-feng sun, cheng yi, chen-yu yang, ke-liang chen, xiao-wei zhang, yun-bao liu*, phytochemistry, 2023, 209, 113625.
3. undescribed meleagrin alkaloids from the endophytic fungus penicillium commune. hai-yan cao, jing-yi zhao, cheng yi, sen-feng sun, ke-liang chen, zhi-min qin, yun-bao liu*, phytochemistry, 2022, 204, 113441.
4. anti-inflammatory dimeric tetrahydroxanthones from an endophytic muyocopron laterale. hai-yan cao, cheng yi, sen-feng sun, yong li, yun-bao liu*, journal of natural products, 2022, 85, 148-161.
5. two sydowic acid derivatives and a sulfonyl metabolite from the endophytic fungus aspergillus sydowii. ke-liang chen, sen-feng sun, hai-yan cao, cheng yi, chen-yu yang, yun-bao liu*, journal of natural products, 2022, 24, 1128-1133.
6. secondary metabolites with diversified structures from an endophytic fungus colletotrichum gloeosporioides associated with a toxic medicinal plant tylophora ovata. sen-feng sun, hai-yan cao, cheng yi, shao zhu, zhi-min qin, yun-bao liu*, journal of natural products, 2022, 24, 468-482.
7. brusatol derivative-34 attenuates allergic airway inflammation via inhibition of the spleen tyrosine kinase pathway. ya-si ding, wei-bin tang, fei pei, li-xia fu, pei ma, jin-ye bai, ming-bao lin*, yun-bao liu*, qi hou*, frontiers in pharmacology, 2021, 30, 587417.
8. fungi: outstanding source of novel chemical scaffolds. zhen liu, jing-yi zhao, sen-feng sun, yong li, yun-bao liu*. journal of asian natural products research, 2020, 22, 99-120.
9. nonadride and spirocyclic anhydride derivatives from the plant endophytic fungus talaromyces purpurogenus, jing-yi zhao, xiao-jing wang, zhen liu, fan-xing meng, sen-feng sun, fei ye, and yun-bao liu*. journal of natural products, 2019, 82, 2953-2962.
10. sesquiterpenes from an endophytic aspergillus flavus，zhen liu, jing-yi zhao, sen-feng sun, yong li, jing qu, hai-tao liu, and yun-bao liu*, journal of natural products, 2019, 82, 1063-1071.
11. dothiorelone derivatives from an endophyte diaporthe pseudomangiferaea inhibit the activation of human lung fibroblasts mrc-5 cells, zhen liu, jing-yi zhao, xiao liang, xiao-xi lv, yong li, jing qu, yun-bao liu*. fitoteropia, 2018, 127, 7-14.
12. sesquiterpenes from the endophyte glomerella cingula, yun-bao liu, yong li, zhen liu, li li, jing qu, shuang-gang ma, ri-dao chen, jun-gui dai, and shi-shan yu*, journal of natural products, 2017, 80, 2609-2614.
13. antiviral spirotriscoumarins a and b: two pairs of oligomeric coumarin enantiomers with a spirodienone−sesquiterpene skeleton from toddalia asiatica，zhong-hai tang#, yun-bao liu#, shuang-gang ma#, li li, yong li, jian-dong jiang, jing qu*, and shi-shan yu*, organic letters, 2016, 18, 5146-5149.
14. metabolites produced by the endophytic fungus aspergillus fumigatus from the stem of erythrophloeum fordii oliv，yu-sheng shi, yan zhang, xiao-zhong chen, ning zhang and yun-bao liu*，molecules, 2015, 20, 10793-10799.
15. eremophilane sesquiterpenes and polyketones produced by an endophytic guignardia fungus from the toxic plant gelsemium elegans, yun-bao liu, yong li, jing qu, shuang-gang ma, cai-xia zang, yu-tian zhang, and shi-shan yu*, journal of natural products, 2015, 78, 2149-2154.
16. mollanol a, a diterpenoid with a new c‒nor‒d‒homograyanane skeleton from the fruits of rhododendron molle，yong li#, yun-bao liu#, yang-lan liu, chen wang, lian-qiu wu, li li, shuang-gang ma, jing qu, and shi-shan yu*, organic letters, 2014, 16, 4320-4323.
17. chiral resolution and absolute configuration of a pair of rare racemic spirodienone sesquineolignans, yu-sheng shi#, yun-bao liu#, yong li, li li, jing qu, shuang-gang ma, and shi-shan yu*, organic letters, 2014, 16, 5406-5409.
18. structures and absolute configurations of penicillactones a-c from an endophytic microorganism, penicillium dangeardii pitt, yun-bao liu#, guang-zhi ding#, yong li, jing qu, shuang-gang ma, hai-ning lv, yang liu, wen-jie wang, jun-gui dai, yi tang, shi-shan yu*, organic letters, 2013, 15, 5206-5209.
1. 天然药物精准研发，主编：庾石山；副主编：陈晓光、石建功、刘云宝；编委：胡卓伟、尹大力、刘玉玲、胡友财、李平平、张丹、鲍秀琦、吴连秋、张晓伟。上海交通大学出版社，2021年
1. 一种角蛋白bd-14、制法和其药物组合物与用途。庾石山，王晓良，刘云宝，苏国柱，李密，徐少锋，张咪，蔡杰。专利号：zl201911028739.2。授权日：2023年9月26日。
2. 一种角蛋白bd-6、制法和其药物组合物与用途。庾石山，王晓良，史国茹，刘云宝，李勇，王玲，李江，冯楠，李密。专利号：zl201911028712.3。授权日：2023年9月26日。
3. 一种角蛋白bd-10、制法和其药物组合物与用途。庾石山，王晓良，符江，刘云宝，冯楠，张咪，史国茹，蔡杰。专利号： zl201911028718.0。授权日：2023年9月26日。
4. 一种角蛋白bd-11、制法和其药物组合物与用途。庾石山，王晓良，符江，李勇，张咪， 冯楠，苏国柱，李江，刘云宝。专利号：zl201911028747.7。授权日：2023年9月26日。
5. 一种角蛋白bd-15、制法和其药物组合物与用途。庾石山，王晓良，李勇，屈晶，蔡杰，徐少峰，刘云宝，张咪。专利号：zl201911028705.3。授权日：2023年9月26日。
6. 一种角蛋白bd-13、制法和其药物组合物与用途。庾石山，王晓良，符江，李勇，张咪，冯楠，苏国柱，李江，刘云宝，屈晶，李江，冯楠，李勇，张咪，苏国柱。专利号：zl201911028760.2。授权日：2023年9月26日。
7. 人工熊胆及其制备方法。庾石山，王晓良，李勇，屈晶，马双刚，刘云宝，王玲，徐少峰，冯楠，李江，徐孝先，张和平，郭经。授权日：2023年2月16日。
8. 光学纯（s）-3-新戊酰氧基-6，7-二甲氧基菲并吲哚里西啶的制备。庾石山，王汝冰，吕海宁，徐嵩，马双刚，刘云宝。专利号：zl201810235803.3。授权日：2022年1月11日。
9. 3-酰氧基取代右旋去氧娃儿藤宁衍生物、其制法和药物组合物与用途。庾石山，陈晓光，吕海宁，李超，徐嵩，刘云宝，马双刚，李勇。专利号：zl201310467212.6。授权日：2019年1月1日。
10. 抗柯萨奇病毒的二萜酸及其制法和其药物组合物与用途。庾石山，蒋建东，张贵杰，李玉环，屈晶，马双刚，刘云宝，李勇。专利号：zl201210171961.x。授权日：2016年12月14日。
2020年度北京市科学技术进步奖一等奖，有毒中药活性成分研究与质量安全标准制定及应用，庾石山、张东明、张聿梅、陈晓光、李勇、马双刚、刘云宝、屈晶、侯琦、张丹。
